In You, Me and Him we meet lesbian couple Olivia and Alex (Lucy Punch, Faye Marsay) who, despite their age difference, are very much in love. But as the question of pregnancy rears its head and their neighbour John (David Tennant) befriends them, they both start making some truly disastrous decisions.

Early 20th century England: while toasting his daughter Catherine's engagement, Arthur Winslow learns the royal naval academy expelled his 14-year-old son, Ronnie, for stealing five shillings. Father asks son if it is true; when the lad denies it, Arthur risks fortune, health, domestic peace, and Catherine's prospects to pursue justice. After defeat in the military court of appeals, Arthur and Catherine go to Sir Robert Morton, a brilliant, cool barrister and M.P., who examines Ronnie and suggests that they take the matter before Parliament to seek permission to sue the Crown. They do, which keeps Ronnie's story on the front page and keeps Catherine in Sir Robert's ken.

Taking place over twenty four hours, the story centres on Will Fletcher, a passionate musician, and Eve Fisher, a beautiful, free-spirited woman who works in the local bar. Whilst struggling to cope with a tragic secret, Will saves Eve from a drunken customer at closing time and their paths become inextricably linked. Intrigued by one another, they journey through London, not knowing what the night holds or what the day may bring. As dawn turns to light and the two draw ever closer, can Will reveal the truth to Eve?

As the new night nurse at a soon to be abandoned children's hospital readies the last group of orphans to leave, it becomes increasingly clear that these are not normal children. Something living in the hospital, something the children call the "mechanical girl," has a terrifying hold over them and will stop at nothing to keep them in the hospital with her forever.

In nineteenth century Yorkshire wealthy orphan Anne Lister lives with an aunt and uncle, anxious for her to marry well and blissfully - unaware that she is a lesbian. Anne is recording her thoughts and exploits in a coded diary. When her lover Mariana Belcombe makes a marriage of convenience to rich old Charles Lawton she feels betrayed and, although Mariana visits her,the relationship is going nowhere. Helped by old flame Tib she makes a play for innocent Miss Browne but sees she is barking up the wrong tree and diverts herself by renovating the family hall. A drunken Tib almost exposes her secret and scornful mine-owner Christopher Rawson, whose marriage proposal she rejects, tells her that her sexuality is a subject of local gossip....

John Halder is a 'good' and decent individual with family problems: a neurotic wife, two demanding children and a mother suffering from senile dementia. A literary professor, Halder explores his personal circumstances in a novel advocating compassionate euthanasia. When the book is unexpectedly enlisted by powerful political figures in support of government propaganda, Halder finds his career rising in an optimistic current of nationalism and prosperity. Seemingly inconsequential decisions lead to choices, which lead to more choices... with eventually devastating effect.

Retired CIA Black-Ops hit man James Jackson Dial is living his life in seclusion on his ranch in Montana when he is offered the chance to redeem himself by his former employer, Jeremy Collins. A few years ago, Dial was seconds away from taking down notorious terrorist cell leader Ali Mahmoud Jahar when when his carelessness allowed Jahar to escape, marking his mission as a failure. Now, Collins wants Dial to eliminate Jahar, who has been captured and is now in the custody of the police in London, England. Provided with a safe house, passports, and an assistant named Terry Winchell, Dial is off to London to finish what he started years ago. Disguised as a priest, Dial gets in position in a church's bell tower across the street from the building that Jahar is being brought into. When Jahar is brought out of his transport truck, his head is covered by a jacket, leaving Dial without a clean shot...