A comedy about a small New Jersey town on the night of Orson Welles' legendary 1938 "War of the Worlds" radio broadcast, which led millions of listeners to believe the U.S. was being invaded by Martians.

The film follows a mountain man on the run from authorities who survives the winter by breaking into empty vacation homes. He's haunted by a recurring dream of being lost at sea and constantly has flashbacks of his former life of a family man.

In a rural Appalachian community haunted by the legacy of a Civil War massacre, a rebellious young man struggles to escape the violence that would bind him to the past.

In Los Angeles, the police put a residential building in quarantine. Meanwhile, the flight attendants of Trans Sky Air, Jenny and Paula, are welcoming the passengers of flight TS Air 318 from Los Angeles to Kansas City with Captain Forrest and Co-Pilot Wilsy. Teacher Henry brings a cage of hamsters to the cabin, but Jenny tells him that it should be transported in the cargo hold. However, one hamster bites the fingertip of the fat passenger Ralph. Soon, Ralph vomits and becomes aggressive, attacking Paula. The male passengers help Jenny and lock Ralph in the bathroom while Captain Forrest requests an emergency landing. When they land in the airport, they find all the gates closed and the Captain heads the plane to an abandoned terminal. Employee Ed helps the crew and passengers to reach the exit, but they find that they are closed. Soon they discover that the place is in quarantine and there is no way out.