A couple who keeps their sick son in a secluded environment find their controlled lives challenged by a young girl who moves in next door.

The basketball coach Clyde and his wife Stephanie divorced a couple of months ago and their teenage daughter Hannah and the girl Emily 'Em' live with their mother and spend the weekends with their father. One day, Clyde stops his car in a yard sale and Em buys an antique carved box and becomes obsessed with it. Em finds the hidden lock and releases an evil spirit that possesses her. Soon Clyde discovers that Em has a problem, but his annoying ex-wife and her boyfriend Brett do not pay attention to him and get a restraining order against Clyde. Clyde seeks out Professor McMannis and when he sees the box, he explains that it is a Dibbuk Box, where a fiend is trapped inside. He also explains that the box should not be open; otherwise the person will be possessed by the spirit. Now Clyde travels to a Jewish community in New York and the rabbi's son Tzadok returns with him expecting to exorcise Em to save the girl.

Big city girl Caroline is new to a small town, she disregards her high school classmates, and then just for kicks starts a sexual relationship with her teacher, Mr. A. Meanwhile, there's a serial killer roaming the town, an industrial fire burning on the outskirts, and Thurston is mourning the loss of his best friend. As Thurston falls in love with Caroline, realities quickly catch up to all characters, and they are all going to have mature or face the consequences.