Mary, a new mother, gives birth to twins, but only one of them is alive. While taking care of her living child, Adam, she suspects that something, a supernatural entity, has chosen him and will stop at nothing to take him from her.

In this modern update of the Hansel and Gretel fairy tale (actually more like Gretel and Gretel), 15-year old Crystal is a bulimic delinquent who makes her living by beating and robbing potential "tricks". While awaiting a 25-year jail term, Crystal hooks up with a psychotic young lesbian named Cyclona, doing time for slaughtering her entire family. After escaping, they head for Mexico, where Cyclona's saviour Sister Gomez lives in a confectionery full of children. Along the way, they leave a trail of crack rocks, binging and purging, and dead people.