Not for Nothing is a "follow your dreams" comedy about Steve, a first generation Italian-American wishing to become a head chef against his father's blue-collar judgment. Unfortunately, Steve doesn't have a culinary degree, so his dream quickly hits a brick wall and in order to pay the bills, he takes a job with a package delivery service. Initially embarrassed by his new 9-to-5 existence, Steve soon learns there is more than one way to pursue your dreams and the answers to life's toughest questions are found when you stop looking for them.

New York postal worker Jacob Singer is trying to keep his frayed life from unraveling. His days are increasingly being invaded by flashbacks to his first marriage, his now-dead son, and his tour of duty in Vietnam. Athough his new wife tries to help Jacob keep his grip on sanity, the line between reality and delusion is steadily growing more and more uncertain.

In Manhattan, Genevieve Gernier owns a flower shop and has a personal dating rule: a limit of five dates with a man to avoid a relationship. When Greg Gatlin buys a restaurant nearby her shop, they decide to date. However, after five dates, Genevieve is not happy with her rule and does not know how to meet Greg again.