Southern California high school senior Carson arrives at the all-important "Cheer Camp Nationals" determined to lead her squad, the West High Sharks, to victory. But chic New Yorker Brooke and her team, the East High Jets, are equally steadfast in their pursuit of the competition's coveted "Spirit Stick." As tension mounts between the two rival squads, Carson falls for fellow cheerleader Penn, not realizing he's a Jet. When Brooke discovers the budding romance, she raises the stakes by challenging Carson to a one-on-one cheer-off. A spectacular "cheer fighting" sequence erupts into a no-holds-barred brawl and cheerleaders on both sides are suspended from the competition. With their dreams of taking home the top prize all but shattered, the leaders of both squads realize they'll have to take drastic measures to stay in the game.

When a street smart "goth girl" (Roxy Vandiver) is forced to attend cheerleader camp as part of her rehabilitation from a juvenile correction facility, she clashes with the "popular girls," and finds herself embroiled in a bitter rivalry with the bitchy ringleader Rachel (Julin). But when members of the spirit squad start turning up dead, the girls must put aside their differences and struggle to survive the murderous rage of a crazed psycho-killer lurking among them!

Two guys, Nick and Shawn decide a two week stint at a Cheerleaders' Camp is the perfect opportunity to score tons of meaningless romantic liaisons with lonely girls in tight-tops and short-short skirts. But their lusty plan to caress as many pom-poms as possible goes awry when one of the dudes fall in love.