Now come into his full knowledge and power, the Anti-Christ in the body of Damien Thorne is about to strike his final blow. The Christ-child has been born again, on the Angel Isle, Great Britain (Scotland, England & Wales). The plan is simple, find the male children born on the specified day, and kill them all.

Seven years later, 13-year-old Damien is just discovering who he really is, and what he is destined to do. Now living with his Aunt, Uncle, and cousin in a wealthy suburb of Chicago, Damien is anxious to inherit everything. Can Richard Thorn finish the job that Damien's father (Ambassador Thorn) started?

When the Vatican observatory priest sees the appearance of a comet, the Church is sure that it confirms the eve of the Armageddon. Meanwhile, the USA President's godson Robert Thorn is informed in the maternity in Rome by Father Spiletto that his wife Katherine has just lost her baby and she had troubles with her uterus and would not have another pregnancy. Spiletto suggests Robert that another just born child that lost his mother could be the substituted for his son, and Robert accepts the child and gives the name of Damien. Robert is promoted to ambassador in London after a tragic accident. When Damien's nanny commits suicide in his birthday party, a substitute, Mrs. Baylock, comes to work and live with the family. Along the years, Katherine realizes that Damien is evil, while Robert is contacted by Father Brennan, who tells him that Damien is the son of devil. When the priest dies in a bizarre accident...

In Bucharest, Allison is protecting the mysterious bible, "The Prophet Lexicon", where the last chapter about the apocalypse, called Revelations, discloses the name of the Antichrist in its last page. Meanwhile, the evil and jealous leader of the renegade angels Thrones, Stark, forces the hit-man Dylan to kill Allison to get the information about the Antichrist, but Dylan mysteriously feels attracted by the woman, protecting her against the Thrones. Allison seeks John Reigart for help, but Satan tell her that he is interested in the apocalypse to gather millions of souls to Hell. Alone and betrayed, Allison discloses the truth about her origins, while protecting the Lexicon.