During a gala museum event featuring precious Vatican artifacts, a group of men posing as Templar knights stage a daring robbery. Their primary interest is in obtaining a mechanical decoding device that can supposedly decipher the location of the Templar treasure. Archaeologist Tess Chaykin reluctantly works with FBI Agent Sean Daley to uncover the mastermind behind the plot and possibly locate the treasure.

ANNA is an ambitious young archaeologist. She desperately needs the kudos of an important find. But her work is ruined when the authorities suddenly shut down the old hospital in which she is working. Plague spores contaminate its medieval foundations. ANNA is convinced that this ancient plague site holds an even darker secret. In her research she has stumbled on a murderous pattern of unexplained child deaths. This is a very cold case; the children disappeared in 1665, the year of the GREAT PLAGUE. The 'suits' at her museum don't buy her theories and they give the go-ahead for the hospital's imminent demolition. That night ANNA risks everything, and breaks back into the hospital to prove her suspicions. Reaching for a mysterious ancient artifact, she slips and falls. Meanwhile, NICK's 21st birthday celebrations are culminating in chaos. He just wanted a good night out with girlfriend JOOLZ...

After two archaeologists discover an ancient alien artifact in Africa, they must run for their lifes from both the unstoppable guardian and protector that awakens as a result, and their greedy, madman employer, both of whom want the artifact.