The Doctor is a renegade Time Lord: an eccentric, highly-intelligent scientist from a distant planet. He travels through time and space in the TARDIS, a curious device, larger on the inside than on the outside, which was designed to change its appearance to suit its surroundings. Unfortunately, the Doctor's TARDIS seems to be broken, and always appears as a blue British police box. The Doctor has a soft spot for the planet Earth, and often visits there, either to save it from various alien threats or to whisk a choice few inhabitants away to the distant parts of the galaxy to help him fight evil there. The Doctor has many foes, including Daleks (led by Davros), and The Master, another renegade Time Lord. Time Lord biology enables them to regenerate their bodies, and so both the Doctor and the Master appear to evolve over the years...

Alicia arrives in South America to vacation with her cousin, Sarah. When Sarah is suddenly called away, Alicia is stuck on a remote island off Chile with three of Sarah's friends, including Brink, an American exchange student with a sadistic streak. Bewildered, frightened, and unable to sleep, Alicia's reality becomes a nightmare from which there is no waking. Ancient indigenous rites, disturbing animal behavior, and captivating hypnotic trances come together in an intense exploration into the darkest corners... when the games go too far, reality unravels with astonishing and deadly consequences.