In a dark and decadent area of São Paulo, the exiled Americans Sinatra and his son Paul own a brothel. Paul is a compulsive gambler addicted in cocaine and his father is married with the former prostitute Angie, and they have a little son. When a client is killed by his wife in their establishment, they find a suitcase with drugs. In the night that they have scheduled a negotiation with African buyers, their African liaison dies while having sex with the travesty Nazda. Sinatra proposes to the Nigerian dishwasher of the brothel, Wemba, to travel to the harbor of Santos, close the business with the drug dealers and in return he would receive a large amount. Wemba accepts but while returning to his car in the harbor, he is attacked by two smalltime thieves and passes out. His lack of contact with Sinatra and Paul leads to a sequence of misunderstandings with a tragic end.

This is the story of a friendship that changes the course of rock history forever, of the fateful collision of minds between JB and KG that led to the creation of the precedent-shattering band Tenacious D, and of the two heroes' quest to find the fabled Guitar Pick Of Destiny...

While practicing motocross in Hawaii, Sean Jones witnesses the brutal murder of an important American prosecutor by the powerful mobster Eddie Kim. He is protected and persuaded by the FBI agent Neville Flynn to testify against Eddie in Los Angeles. They embark in the red-eye Flight 121 of Pacific Air, occupying the entire first-class. However, Eddie dispatches hundred of different species of snakes airborne with a time operated device in the luggage to release the snakes in the flight with the intent of crashing the plane. Neville and the passengers have to struggle with the snakes to survive.

Nacho (Black) is a monastery cook, who spends his day feeding orphans and being overlooked by the monastery. When Sister Encarnación (Reguera) arrive at the monastery, Nacho realises that the only way to win her affection and to save the children, will be by competing as a Luchador wrestler.

In Cayman Island, the daughter of a powerful man - Andrea - and the fisherman Shy are in a deep but secret love, hidden from Andrea's parents. When Andrea's father sails in a fish-trip, they have a night of love at Andrea's home; however they sleep and are surprised by the arrival of her family in the morning. Later, Andrea's brother Hammer throws acid on the face of Shy and spends four months in prison. In Miami, the dirty businessman Carl Ridley is chased by Federal agents and escapes with his teenage daughter Pippa to Cayman Island trying to reach his lawyer Mr. Allen. Pippa meets the small time thief Fritz sleeping in her room and he invites her to go a party. Before leaving the condo, Fritz sees Carl counting lots of money. Fritz owes money to the dangerous drug dealer Richie Rich and tells him about the fortune Carl has. Along a Friday 13th night, their lives entwine in a chain of tragic events.

While recovering from a tragic accident on the road, the patrolman Edward Malus receives a letter from his former fiancée Willow, who left him years ago without any explanation, telling that her daughter Rowan is missing. Edward travels to the private island of Summerisle, where Willow lives in an odd community that plant fruits, and she reveals that Rowan is actually their daughter. Along his investigation with the hostile and unhelpful dwellers, Edward discloses that the locals are pagans, practicing old rituals to improve their harvest, and Rowan is probably alive and being prepared to be sacrificed. When he locates the girl, he finds also the dark truth about the wicker man.

In the 50's, in Louisiana, the smart populist, manipulative and wolf hick Willie Stark is elected governor with the support of the lower social classes. He joins a team composed of his bodyguard and friend Sugar Boy; the journalist from an aristocratic family Jack Burden; the lobbyist Tiny Duffy; and his mistress Sadie Burke, to face the opposition of the upper classes. When the influent Judge Irwin supports a group of politicians in their request of impeachment, Stark assigns Jack to find some dirtiness along the life of Irwin, leading to a tragedy in the end.