Late in 2006, President Jimmy Carter tours the U.S. promoting his provocative "Palestine: Peace Not Apartheid." Demme's camera follows Carter from city to city, home to Plains (population 635), visiting a Habitat for Humanity site in New Orleans, and talking on radio and TV with Teri Gross, Charlie Rose, Diane Rehm, Jay Leno, Larry King, Wolf Blitzer, Tavis Smiley, and Al Jazeera and Israeli pundits, discussing Palestine's plight and the policies of Israel. Critics speak as well. Between events, Carter talks about Camp David, recent travels, being married, speaking Spanish, and wisdom he learned from Rachel Clark, his nanny. A montage of speeches, awards, and travels ends the film.

The crew have now set off to finish what as left over from Jackass 2.0, and in this version they have Wee Man use a 'pee' gun on themselves, having a mini motor bike fracas in the grocery mall, a sperm test, a portly crew member disguised as King Kong, as well as include three episodes of their hilarious adventures in India, namely drinking beer off of Shridhar Chillai's several feet long fingernails; having one of the crew lie on a bed of nails with two snakes - one on his chest and one between the legs, as well as a decorated elephant in the background; and finally having a half-naked Indian Sadhu drink one of the crew's urine.