When the young woman Tristana's mother dies, she is entrusted to the guardianship of the well-respected though old Don Lope. Don Lope is well-liked and well-known because of his honorable nature, despite his socialistic views about business and religion. But Don Lope's one weakness is women, and he falls for the innocent girl in his charge, seduces her, makes her his lover, though all the while explaining to her that she is as free as he. But when she acts on this freedom, Don Lope must deal with the consequences of his world-view.

Viridiana, a young novice about to take her final vows as a nun, accedes to a request from her widowed uncle to visit him. Moved purely by a sense of obligation, she does so. Her uncle is moved by her resemblance to his late wife to attempt to seduce Viridiana, and tragedy ensues. In the aftermath, Viridiana tries to assuage her guilt by creating a haven for the destitute folk who live around her uncle's estate. But from these good intentions, too, comes little good.