Several psychopaths wreak havoc over the course of a violent night.

Zack Connors and Rachel Meadows were born with incredible psychokinetic capabilities. When word of their supernatural talents gets out, they find themselves the prisoners of Michael Slovak, a deranged doctor intent on harvesting their powers. After a daring escape, they are free from his sinister institution, but the corrupt doctor will stop at nothing to track them down so that he may continue to siphon their gifts for his own use.

Two former baseball players, Ben (Jeremy Gardner) and Mickey (Adam Cronheim), cut an aimless path across a desolate New England. They stick to the back roads and forests to steer clear of the shambling corpses that patrol the once bustling cities and towns. In order to survive, they must overcome the stark differences in each other's personalities. Ben embraces an increasingly feral, lawless, and nomadic lifestyle while Mickey is unable to accept the harsh realities of the new world and longs for the creature comforts he once took for granted. A bed, a girl, and a safe place to live. When the men intercept a radio transmission from a seemingly thriving, protected community, Mickey will stop at nothing to find it, even though it is made perfectly clear that he is not welcome.