During a traumatic accident whilst on a deep-sea dive in the depths of the Atlantic Ocean, Olive, a gifted, young marine-biologist discovers an unearthly creature. Loosing her dream job, Olive smuggles the creature home, intent on studying it in her basement, unbeknownst to her devoted boyfriend Matt. Whilst struggling to re-adjust to landlocked life and recover from her recent trauma, Olive begins to realize that she and the creature share a symbiotic bond that drives her to carry out its sinister will. Plagued by gruesome nightmares, her fractured memories of what happened during the accident in the depths of the ocean begin to unravel and reveal an eldritch horror far older and malevolent than she could ever imagine, one which she has unwittingly set free. Olive's obsession leads to madness as her discovery consumes her entire humanity, with deadly results for those around her.

In Los Angeles, the eleven year old Anna Fitzgerald seeks the successful lawyer Campbell Alexander trying to hire him to earn medical emancipation from her mother Sara that wants Anna to donate her kidney to her sister. She tells the lawyer the story of her family after the discovery that her older sister Kate has had leukemia; how she was conceived by in vitro fertilization to become a donor; and the medical procedures she has been submitted since she was five years old to donate to her sister. Campbell accepts to work pro bono and the obsessed Sara decides to go to court to force Anna to help her sister.

Alan Johnson has everything he needs to get through life: a good job, a beautiful and loving wife, and their wonderful children. Yet he feels isolated because he finds having a hard-working job and managing a family too much to handle and has no one to talk to about it. Charlie Fineman, on the other hand, doesn't have a job or a family. He used to have both until a terrible loss, and the grief caused him to quit his job and isolate himself from everyone around him. As it turns out, Alan and Charlie were roommates in college, and a chance encounter one night rekindles the friendship they shared. But when Charlie's problems become too much to deal with, Alan is determined to help Charlie come out of his emotional abyss.