"American Pop" is the animated story of a very talented and troubled family starting with 19th century Russia and moving through several generations of musicians. The film covers American music from the pre-jazz age through soul, '50s rock, drug-laden psychadelia, and punk, finally ending with the onset of new wave in the early 1980s.

Harry Bailey has returned from Vietnam and returns to college to earn his masters degree so he can teach English. He is considered a hero among the radical student body, but still sees the absurdity on both sides of the fence. He contends with the reactionary administration and the impetuous, often futile objectives of the restless students. He acts as a mediator between the two feuding bodies. On top of everything else, his girlfriend Jan wants to marry him and live a life in the suburbs. He is cornered and finally lets loose at his own masters degree dissertation meeting, just as the latest protest heats up.