Monco is a bounty killer chasing El Indio and his gang. During his hunting, he meets Col. Douglas Mortimer, another bounty killer, and they decide to make a partnership, chase the bad guys together and split the reward. During their enterprise, there will be lots of bullets and funny situations. In the end, one of the bounty hunters shows the real intention of his hunting.

Blondie (The Good) is a professional gunslinger who is out trying to earn a few dollars. Angel Eyes (The Bad) is a hit man who always commits to a task and sees it through, as long as he is paid to do so. And Tuco (The Ugly) is a wanted outlaw trying to take care of his own hide. Tuco and Blondie share a partnership together making money off Tuco's bounty, but when Blondie unties the partnership, Tuco tries to hunt down Blondie. When Blondie and Tuco come across a horse carriage loaded with dead...