Simon, a deeply religious man living in the 4th century, wants to be nearer to God so he climbs a column. The Devil wants him come down to Earth and is trying to seduce him. But Simon recognizes him everytime. So the Devil takes him to a nightclub in New York of the 1960s.

Viridiana, a young novice about to take her final vows as a nun, accedes to a request from her widowed uncle to visit him. Moved purely by a sense of obligation, she does so. Her uncle is moved by her resemblance to his late wife to attempt to seduce Viridiana, and tragedy ensues. In the aftermath, Viridiana tries to assuage her guilt by creating a haven for the destitute folk who live around her uncle's estate. But from these good intentions, too, comes little good.

After a lavish dinner party, the guests find themselves mysteriously unable to leave the room... and over the next few days all the elaborate pretenses and facades that they've built up by virtue of their position in society collapse completely as they become reduced to living like animals...