A gangster, a crooked banker, a hitman and an arab terrorist are stranded and on the run in a small village in South America. Their only chance of escape is to drive two trucks filled with unstable nitroglycerin up a long and rocky mountain road in order to plug an escalating oil refinery blaze. With their deadly cargo likely to explode at the slightest bump, the four men must put aside their differences and work together to survive.

The futility and irony of the war in the trenches in WWI is shown as a unit commander in the French army must deal with the mutiny of his men and a glory-seeking general after part of his force falls back under fire in an impossible attack.