A simple stagecoach trip is complicated by the fact that Geronimo is on the warpath in the area. The passengers on the coach include a a drunken doctor, two women, a bank manager who has taken off with his client's money, and the famous Ringo Kid, among others.

Wyatt Earp and his brothers Morgan and Virgil ride into Tombstone and leave brother James in charge of their cattle herd. On their return they find their cattle stolen and James dead. Wyatt takes on the job of town marshal, making his brothers deputies, and vows to stay in Tombstone until James' killers are found. He soon runs into the brooding, coughing, hard-drinking Doc Holliday as well as the sullen and vicious Clanton clan. Wyatt discovers the owner of a trinket stolen from James' dead body and the stage is set for the Earps' long-awaited revenge.

Fred C. Dobbs and Bob Curtin, both down on their luck in Tampico, Mexico in 1925, meet up with a grizzled prospector named Howard and decide to join with him in search of gold in the wilds of central Mexico. Through enormous difficulties, they eventually succeed in finding gold, but bandits, the elements, and most especially greed threaten to turn their success into disaster.