A powerful action thriller, ARSENAL tells the intertwining stories of the Lindel brothers, Mikey (Johnathon Schaech) and JP (Adrian Grenier), who had only each other to rely on growing up. As adults, JP found success as the owner of a construction company, while Mikey became a small-time mobster, mired in a life of petty crime. When Mikey is kidnapped and held for a ransom by ruthless crime boss Eddie King (Nicolas Cage), JP turns to the brothers' old pal Sal (John Cusack), a plain clothes detective for help. In order to rescue his brother, JP must risk everything and unleash his vengeance against King's relentless army of gangsters.

Harry Turner works for the CIA like his father Leonard. He wants to do fieldwork but he's constantly being denied. He is stationed in Prague and his father's good friend keeps an eye on him. Later they receive word that Leonard, who was in New Jersey making sure a piece of hardware called Condor arrives, that Leonard and the Condor's been taken. The Director tries to find it and Harry wants to help but won't let him. So he bolts and goes to New Jersey. The director decides to let one of their agents who is Harry's ex to find Leonard and the Condor. She was also told to find Harry and send him back to Prague. But when she finds him, he convinces her to let him find his father and the Condor.

Successful writer and scholar Jonathan Merrick falls under the spell of the irresistible, bewitchingly beautiful Ligeia. She's fighting a fatal illness and she will stop at nothing to defeat death, her one true enemy. She steals other people's souls and on her quest to immortality she tricks Jonathan into supporting her work, breaking him apart from his fiancé Rowena and pulling him into her dark, mysterious world. They settle down in an old manor by the Black Sea where Ligeia's everlasting presence slowly drives Jonathan to madness...