A group of friends pays a late-night visit to the city morgue to surprise Amy (Harris) on her birthday. But the surprise is on them when the one-eyed corpse of brutal psychopath Jacob Goodnight (Jacobs) unexpectedly rises from a cold sub-basement slab. Their wild party quickly turns into a terrifying slay-fest as the sadistic mass-murderer resumes his savage rampage complete with hooks, surgical knives and power saws.

In order to see magic idol Krell Darius perform his world-famous magic act, a beautiful aspiring young-magician, Tatiana, travels from New York to Las Vegas with her closest friends, BFFs, Elena and Vera. As the layers of illusion unfold, so too do the dark windows into Tatiana's past.

Their vengeance is relentless, their method is ritual, their weapon is secret, and the motive is in their blood. In a heavily wooded private estate in the Malibu Hills, towering above the tumbling Pacific, millionaire CEO Kenji Takeo and his daughter, Miko, prepare for the arrival from Japan of Takeo's wife, Kumiko. But the calm of Solstice Canyon is shattered by a meticulously planned stealth attack on the Takeo home by a masked band of ninja assassins. In a flash, Takeo's guards are killed. The mansion is overtaken, Takeo is killed, and Miko is left for dead. Arriving at the bloody scene is Detective Jack Barrett who encounters Miko-the only living witness. In a state of shock, she repeats only one word like an eerie mantra: kokushibyu. In her native language, it means Black Death.

While investigating a call in an abandoned house, Officer Frank Williams and a rookie find a woman brutally blinded, but they are attacked by a huge psychopath with an ax; the rookie is killed and Frank shots the criminal in the head, but has a severed arm. Four years later, the mutilated Frank is relocated, working as a guard in the County Detention Center. Frank goes with some delinquents to the Blackwell Hotel, an abandoned place since a fire burnt the last two floors, with the purpose of cleaning the location, preparing it to work as a shelter for homeless; in return, the criminals will have their sentences reduced. During the night, the inmate Kira that has some Christian tattoos in her body is kidnapped by the deranged serial-killer Kane that collect the eyes of his victims, while the rest of the group is attacked by the psychopath with his ax.