Jacob Bradley wakes up in a warehouse in the midst of a tactical raid, with no memory and no idea who he is. He is found by a young woman who helps him escape, and tells him that no matter what happens, he must survive. A terrorist organization is on the cusp of releasing a virus. They have provided the antidote to only a select few, to ensure the recreation of a utopian world and before he lost his memory, Jacob was one of the few people who had discovered the details. If they are to survive, he needs to rebuild the pieces of his past. They find themselves in a race for survival, for themselves and the rest of mankind, that will demand everything they have, and reveal that Jacob has always been closer to the truth then anyone ever thought.

Fifteen years after Clear Lake, WI was evacuated and quarantined by the government, four young adults return to the small town in search of clues about their mysterious past. Back in 1994, a mysterious virus appeared in Clear Lake. As panic spread, a local priest (Michael Madsen) convinced a small group of high school students that the locals were being punished by God, and that the day of retribution had finally arrived. It was their job, claimed the priest, to apprehend the worst sinners, and ensure that they suffered for their transgressions. When government health officials arrived to investigate, they were shocked to discover that 13 of the locals had vanished without a trace, and the majority of the townspeople had abandoned their homes for fear of getting infected. For the following 15 years, the town sat eerily still and completely unoccupied. Now, a group of documentary filmmakers have convinced the kids who previously took part in the kidnappings to return to Clear Lake...

A week before Christmas a viral outbreak turns the citizens of Los Angeles into the walking dead. On the brink of severing ties with both his wife and longtime partner, L.A.P.D. officer Frank Talbot finds himself trapped with them. As death closes in their survival is further threatened by the fact that both men love the same woman.

Patient Zero is a stewardess, stricken with what she thinks is chickenpox. She goes to ground in a Montreal hotel room. A few weeks later, she's back on the job, unaware of her role in an impending public health catastrophe. Pandemics have killed more people throughout history than all wars combined. They are unpredictable - and inevitable. Are we ready for the next big one? Outbreak: Anatomy of a Plague juxtaposes a 21st century scenario against the little-known story of the 1885 smallpox epidemic that devastated Montreal. Combining brisk narrative with rigorous research, it vividly evokes a modern city under siege, drawing eerie parallels with 1885. Confronted with social unrest, ethnic scapegoating and economic ruin, authorities struggle to maintain control - and to contain a deadly infection.