Between her best friend moving to Brooklyn, pressure to find employment from her pop (Daniel Baldwin), and juggling romances with an aging rocker boyfriend and a yuppie fling - Cloey is reluctantly plucked from her party girl reality to deal with her own set of common people dilemmas and accomplishments. Scattered with cameos from musicians like Stephen Malkmus (Pavement), live performances by Glass Candy and Starfucker and a soundtrack featuring all local bands, 'City Baby' documents the youth utopia of Portland Oregon, revolving through the lives of a few sexy, style-conscious kids surviving extreme love affairs and complicated friendships.

Jacob is a troubled soul and when his friends pull a prank on him in the very place his father was killed, he snaps, grabs an ax and hunts them down like animals. Trapped inside, they must fight for their lives from this disturbed ax-wielding maniac.

Kip's perfect life is put in jeopardy when the waitress with whom he's having a casual fling is accidentally killed in their motel room. Desperate, he turns to childhood friend and loser, Marvin, to help get rid of the body. Marvin agrees which begins the unraveling of their friendship and ultimately leads both to murderous acts they never thought themselves capable of.

Claire is about to get married and she goes to Las Vegas with her sister and two friends for her bachelorette party. Things quickly spiral out of control.

16 year old street-wise Apple (Vanessa Hudgens) has never had an easy life. Her mother, June Bailey (Rosario Dawson), is an addict and prostitute, is verbally and physically abusive, and is grooming her daughter to follow in her footsteps. Apple knows the streets, alleys and motels like the back of her hand but wants more from her life. She possesses a tenacious, tough, indomitable spirit, and will not surrender to fate. Apple runs away from her mother and tracks down her father whom she has never known, as he was only 19 when he got Apple's mother pregnant. Apple begs her now Wall Street Broker father, Tom Fitzpatrick (Brendan Fraser), to take her in. In the few days under her father's care, she learns she's become pregnant by a kid from the streets she met on the train, who now wants nothing to do with her. She is forced to leave her father's home because of her choice to give birth to the baby she is carrying. Apple runs away again, and is eventually taken under the wing of Father ...

Eminent Boston Psychiatrist, Frasier Crane, last seen gracing the bars of Cheers has left his life there to start afresh in Seattle. He now has a spot as a popular radio Psychiatrist, giving him the chance to spread words of wit and wisdom to the masses. He shares his apartment with his retired cop father, Martin, and his father's physical care assistant, Daphne Moon. Add in brother Niles, Eddie the dog, some bizarre situations and plenty of humour and you've got all the ingredients for an excellent show and worthy successor to Cheers.