Cartoonist Winsor McCay agrees to create a large set of drawings that will be photographed and made into a motion picture. The job requires plenty of drawing supplies, and the cartoonist must also overcome some mishaps caused by an assistant. Finally, the work is done, and everyone can see the resulting animated picture.

Charlie is in boot camp in the "awkward squad." Once in France he gets no letters from home. He finally gets a package containing limburger cheese which requires a gas mask and which he throws over into the German trench. He goes "over the top" and captures thirteen Germans ("I surrounded them"), then volunteers to wander through the German lines disguised as a tree trunk. With the help of a French girl he captures the Kaiser and the Crown Prince and is given a statue and victory parade in New York and then ... fellow soldiers wake him from his dream.

A young woman has a peaceful existence, living near the sea and enjoying a romance with a simple, hard-working fisherman. But she finds herself in sudden danger when she happens upon the crew of a boat while they are ashore in the act of smuggling. She is abducted and forced aboard their boat. While the fisherman races to organize a rescue mission, the crew of the boat decides to seize her from the captain, in order to have their way with her.

Roscoe flirts with a girl in the park. Later he takes his wife and mother-in-law to the movies only to see his flirtation showing on the screen.

An American boy turns out to be the long-lost heir of a British fortune. He is sent to live with the cold and unsentimental lord who oversees the trust.

The comfortable and amiable Daniel Boone Brown, a resident of New York's water front, becomes the victim of a mad scientist's psychological experiments. For days, Dr. Ulrich Metz messes up Daniel's life, bringing on failing health, restless sleep, a nervous and irritable disposition, tardiness for work, and superstitions that cause worry and fear. Several months into the ordeal, one of Metz's minions, hired as Daniel's livery, feeds him a midnight snack of spring onions, lobster, Welsh rarebit and mince pie. We see the contents of his stomach causing pain and distress; then he has vivid and surreal nightmares. Will Metz succeed in driving Daniel to suicide?

A young man can only get the woman he loves if he becomes famous and manages to get his picture in the newspapers. He determines to let nothing stand in the way of his doing exactly that, and in the process winds up getting involved with a gang of criminals and a locomotive chase.

Dr. Henry Jekyll experiments with scientific means of revealing the hidden, dark side of man and releases a murderer from within himself.

In a strange grotto deep in the bowels of the earth a coffin uprights itself, dances, then opens, and out steps a demonic magician with skeletal face, horns, and cape. He wraps two women (who appear to be in a trance) in fabric, levitates them, and causes them to burst into flames and disappear. As he gathers their ashes in a pitcher a Good Spirit [a young woman who resembles Peter Pan] appears, shakes her head No, and reveals the "souls" of the two women in a secret compartment deeper within the cave. The Good Spirit vanishes in a puff of smoke. The magician then produces 3 glass bottles on pillars, takes them downstage close to the camera, and reveals 3 tiny women in them; one woman beats a tambourine while the other two sway. The magician pours ashes (?) into the bottles, but the Good Spirit reappears and makes these trapped figures disappear in a flash, angering the magician...

John Howard Payne leaves home and begins a career in the theater. Despite encouragement from his mother and his sweetheart, Payne begins to lead a life of dissolute habits, and this soon leads to ruin and misery. In deep despair, he thinks of better days, and writes a song that later provides inspiration to several others in their own times of need.

Coke Ennyday, the scientific detective, divides his own time in periods for "Sleep", "Eat", "Dope" and "Drink". In fact he's used to overcome every situation with drugs: consuming it to increase his energies or injecting it in his opponents to KO them. To help the police he discovers a contraband of opium (which he eagerly tastes) transported with "Leaping Fishes", and the blackmail of a mysterious man who wants to marry the "fish blower" girl. Will Coke be able to free the girl ?

Winsor Z. McCay bets another cartoonist that he can animate a dinosaur. So he draws a big friendly herbivore called Gertie. Then he get into his own picture. Gertie walks through the picture, eats a tree, meets her creator, and takes him carefully on her back for a ride.

When her father becomes ill, a young woman takes over the telegraph at a lonely western railroad station. She soon gets word that the next train will deliver the payroll for a mining company. The train brings not only the money, but a pair of ruffians bent on stealing it. All alone, she wires for help, and then holds off the bad guys until it arrives.