Within the course of a night, Woody Harrelson finds himself in a misadventure in London that winds him up in prison.

Juggling some angry Russians, the British Mi5, his impossibly leggy wife and an international terrorist, debonair art dealer and part-time rogue Charlie Mortdecai must traverse the globe armed only with his good looks and special charm in a race to recover a stolen painting rumored to contain the code to a lost bank account filled with Nazi gold.