It's Christmas time and the Griswolds are preparing for a family seasonal celebration, but things never run smoothly for Clark, his wife Ellen and their two kids. Clark's continual bad luck is worsened by his obnoxious family guests, but he manages to keep going knowing that his Christmas bonus is due soon.

'Toon star Roger is worried that his wife Jessica is playing pattycake with someone else, so the studio hires detective Eddie Valiant to snoop on her. But the stakes are quickly raised when Marvin Acme is found dead and Roger is the prime suspect. Groundbreaking interaction between the live and animated characters, and lots of references to classic animation.