Kaneda is a bike gang leader whose close friend Tetsuo gets involved in a government secret project known as Akira. On his way to save Tetsuo, Kaneda runs into a group of anti-government activists, greedy politicians, irresponsible scientists and a powerful military leader. The confrontation sparks off Tetsuo's supernatural power leading to bloody death, a coup attempt and the final battle in Tokyo Olympiad where Akira's secrets were buried 30 years ago.

Four middle-aged men decide to take a road trip from Cincinnati to the Pacific in order to get away from their lives which are leading them nowhere. Taking their motorcycles, these "Wild Hogs" tear up the road and eventually stop in New Mexico for a drink not knowing that the bar belongs to the "Del Fuegos", a mean biker gang. When the Del Fuegos steal a bike that belongs to the Wild Hogs, the four men form a plan to steal their bike back.