In the crime world of Colombia, there is an unwritten code. When Víctor and Eusebio, two hoods who bungle a shake-down job, break that code, they unwittingly sign their own death sentence.

Comedy veterans and co-creators Penn Jillette and Paul Provenza capitalize on their insider status and invite over 100 of their closest friends--who happen to be some of the biggest names in entertainment, from George Carlin, Whoopi Goldberg and Drew Carey to Gilbert Gottfried, Bob Saget, Paul Reiser and Sarah Silverman--to reminisce, analyze, deconstruct and deliver their own versions of the world's dirtiest joke, an old burlesque too extreme to be performed in public, called "The Aristocrats."

Fran Garrison's all in a tizzy because her prize Dachshund, Danke, is having pups, and she has hopes of one of the pups becoming a champion. But at the vet's, her husband Jim is talked into letting Danke wetnurse a Great Dane pup that's been abandoned by his mother. And Jim wants to keep the Great Dane. But Brutus has this problem: he thinks he's a dachshund and he's too big to be a lapdog. But when Fran ridicules Brutus one too many times, Jim's got a plan to prove to everyone (and Fran) that a great dane can be far more than just an ugly dachshund.