Tragedy strikes married couple Paul and Lily, when Lily's father dies. Lily has her father cremated, brings the urn home and now Paul has to come to terms with the death of his father-in-law whom he had despised. The situation gets a bit frayed when the lid to the urn mysteriously disappears, and Paul begins to experience happenings no one else is aware of.

An ancient urn is found in a cemetery outside Rome. Once opened, it triggers a series of violent incidents: robberies, rapes and murders increase dramatically, while several mysterious, evil-looking young women coming from all over the world are gathering in the city. All these events are caused by the return of Mater Lacrimarum, the last of three powerful witches who have been spreading terror and death for centuries. Alone against an army of psychos and demons, Sarah Mandy, an art student who seems to have supernatural abilities of her own, is the only person left to prevent the Mother of Tears from destroying Rome.

During a violent thunderstorm, a family is awoken by piercing shrieks which summon the dead to rise again. Their lives explode in a blood soaked fury as they battle malevolent spirits, whilst fighting to save their souls from eternal torment with... the Banshee.