A disturbed young man pairs up with his grumpy grandfather for a road trip in search of his father who left town after digging up the corpse of his wife.

A tough undercover cop inadvertently gets involved in a dangerous heroin ring when a young defector of the drug trade leaves his five year-old sister in his care.

Walrus-like warden, Sven "Swede" Sorenson, a cross between Bluto and Wimpy, runs the prison, murders convicts who escape, and has the FBI on his trail in the form of agent Karen Polarski, the daughter of the town's corrupt judge. Swede's twins tell their father they're pregnant (they aren't), so he pushes their dim boyfriends, Bud and Larry, into shotgun marriages. He also turns his sons-in-law into slave labor, so Bud hatches an escape plan: to rob a train carrying old bills to the mint for burning. Larry's his reluctant accomplice. When Bud is captured and railroaded into Swede's jail, his death looks certain, until he hatches yet another plan that requires Larry's help.

In Manhattan, the successful executive Jack is a methodical and controlled man with simple habits that works in an advertisement agency with his coworker George. While smoking a cigarette on the roof of the building of the agency, Jack meets the aspirant actress Jill that has just arrived in New York and is seeking a job. He sympathizes with her situation and gives her name to a Klubendorf commercial in the campaign promoted by his agency. When he takes Jill home, he finds that she lives in a very low-budget hotel and out of the blue, he invites her to stay in the guest room of his fancy apartment for a while. Jill changes the behavior of Jack that becomes happier, and proposes Jack to write together a manifesto where the first rule is "be honest". However, she omits to Jack that she is sick with cystic fibrosis and she would have only a couple of years more. When Jack discovers that Jill is ill...

Some say that all houses have memories. For one man, his home is the place he would kill to forget. A family unknowingly moves into a home where several grisly murders were committed...only to find themselves the killer's next target. Successful publisher Will Atenton (Craig) quit a job in New York City to relocate his wife, Libby (Weisz), and two girls to a quaint New England town. But as they settle into their new life, they discover their perfect home was the murder scene of a mother and her children. And the entire city believes it was at the hands of the husband who survived. When Will investigates the tragedy, his only lead comes from Ann Paterson (Watts), a neighbor who was close to the family that died. As Will and Ann piece together the disturbing puzzle, they discover that the story of the last man to leave Will's dream house will be just as horrifying to the one who came next.

Boston, 2009. A police detective (Roddy Piper) searches for Adrian Dunn, his ex-partner (Billy Drago) who murdered his wife. Dunn has escaped from prison on the moon and returned to Earth with an alien virus.