Coke Ennyday, the scientific detective, divides his own time in periods for "Sleep", "Eat", "Dope" and "Drink". In fact he's used to overcome every situation with drugs: consuming it to increase his energies or injecting it in his opponents to KO them. To help the police he discovers a contraband of opium (which he eagerly tastes) transported with "Leaping Fishes", and the blackmail of a mysterious man who wants to marry the "fish blower" girl. Will Coke be able to free the girl ?

Buster is playing golf with Sybil when he gets knocked out. An escaped prisoner changes clothes with him. Buster goes to prison and learns that he is to be hanged. He changes clothes with a guard just as prisoner Roberts attacks all the guards.

A young man can only get the woman he loves if he becomes famous and manages to get his picture in the newspapers. He determines to let nothing stand in the way of his doing exactly that, and in the process winds up getting involved with a gang of criminals and a locomotive chase.

The comfortable and amiable Daniel Boone Brown, a resident of New York's water front, becomes the victim of a mad scientist's psychological experiments. For days, Dr. Ulrich Metz messes up Daniel's life, bringing on failing health, restless sleep, a nervous and irritable disposition, tardiness for work, and superstitions that cause worry and fear. Several months into the ordeal, one of Metz's minions, hired as Daniel's livery, feeds him a midnight snack of spring onions, lobster, Welsh rarebit and mince pie. We see the contents of his stomach causing pain and distress; then he has vivid and surreal nightmares. Will Metz succeed in driving Daniel to suicide?

Buster's handmade boat, The Damfino, is finished and is, of course, too large to get through the basement door. When he drives off with it in tow, the side of his house, then the whole thing, collapses. At the harbor he rides the boat out only to have it sink beneath him. The rest is a series of adventures he and his family have with the restored boat.

Roscoe flirts with a girl in the park. Later he takes his wife and mother-in-law to the movies only to see his flirtation showing on the screen.

Charlie is in boot camp in the "awkward squad." Once in France he gets no letters from home. He finally gets a package containing limburger cheese which requires a gas mask and which he throws over into the German trench. He goes "over the top" and captures thirteen Germans ("I surrounded them"), then volunteers to wander through the German lines disguised as a tree trunk. With the help of a French girl he captures the Kaiser and the Crown Prince and is given a statue and victory parade in New York and then ... fellow soldiers wake him from his dream.

A single father struggling to make his comeback as a screenwriter falls in love with one of his students. Meanwhile his son, studying to become a chef, falls in love with his teacher. Love is great for creativity, but it comes with a price.