On the eve of departing for college, Sarah Thompson sets some ground rules for herself in order to attract Mr. Right. But "Life Happens" to the girl who always has a plan and Sarah falls head over heels into the many pitfalls of dating... pitfalls that are probably all too familiar to most of us.

An asteroid named "Matilda" is on a collision course towards Earth and in three weeks the world will come to an absolute end. What would you do if your life and the world were doomed? One man decides to spend his time searching for his long lost love from high school during the coming catastrophe.

Jess - a bubbly offbeat teacher who is known to burst into spontaneous song - catches her boyfriend with another woman, and needs a new place to live. She moves into a loft with three single guys she's never met before. Nick is a jaded law-school dropout, who usually just wants to be left alone. Schmidt is an flashy businessman, who believes he is a gift to women. Winston is a former athlete who doesn't know what to do, but really needs to win whatever it is. Can this dysfunctional group handle the "adorkable" new girl?

Businessman Wesley Deeds is jolted out of his scripted life when he meets Lindsey, a single mother who works on the cleaning crew in his office building.