In 1964, a brash new pro boxer, fresh from his olympic gold medal victory, explodes on to the scene, Cassius Clay. Bold and outspoken, he cuts an entirely new image for African Americans in sport with his proud public self confidence with his unapologetic belief that he is the greatest boxer of all time. To his credit, he sets out to prove that with his highly agile and forceful style soon making him a formidable boxer who soon claims the heavyweight championship. His personal life is no less noteworthy with his allegiance to the Nation of Islam, his friendship with the controversial Malcolm X and his abandonment of his slave name in favour of Muhammad Ali stirring up controversy. Yet, at the top of his game, both Ali's personal and professional lives face the ultimate test with the military draft rules are changed, making him eligible for military induction during the Vietnam War....

When Eastern European criminals Oleg and Emil come to New York City to pick up their share of a heist score, Oleg steals a video camera and starts filming their activities, both legal and illegal. When they learn how the American media circus can make a remorseless killer look like the victim and make them rich, they target media-savvy NYPD Homicide Detective Eddie Flemming and media-naive FDNY Fire Marshal Jordy Warsaw, the cops investigating their murder and torching of their former criminal partner, filming everything to sell to the local tabloid TV show "Top Story."

A modern day look at America's war on drugs told through four separate stories that are connected in one way or another. A conservative politician who's just been appointed as the US drug czar learns that his daughter is a drug addict. A trophy wife struggles to save her husband's drug business, while two DEA agents protect a witness with inside knowledge of the spouse's business. In Mexico, a corrupt, yet dedicated cop struggles with his conscience when he learns that his new boss may not be the anti-drug official he made himself out to be.