In prison and awaiting execution, Dr. Victor Frankenstein recounts to a priest what led him to his current circumstance. He inherited his family's wealth after the death of his mother when he was still only a young man. He hired Paul Krempe as his tutor and he immediately developed an interest in medical science. After several years, he and Krempe became equals and he developed an interest in the origins and nature of life. After successfully re-animating a dead dog, Victor sets about constructing a man using body parts he acquires for the purpose including the hands of a pianist and the brain of a renowned scholar. As Frankenstein's excesses continue to grow, Krempe is not only repulsed by what his friend has done but is concerned for the safety of the beautiful Elizabeth, Victor's cousin and fiancée who has come to live with them. His experiments lead to tragedy and his eventual demise.

Jon Porter returns to his hometown after the sudden and bizarre death of his mother. He hopes to leave as soon as the funeral is over but it's too late. The sinister forces that caused his sister's brutal murder 30 years ago are back. Jon knows the nightmare can't continue. He must stand up to his fear and exorcise the demons who have risen again to take posession of his beautiful teenage daughter - body and soul.

In 1918, an English family are terrorized by a vampire, until they learn how to deal with it. They think their troubles are over, but German bombs in WWII free the monster. He reclaims the soul of his wolfman ex-servant, and assuming the identity of a scientist who has just escaped from a concentration camp, he starts out on a plan to get revenge upon the family.

In the small town of Stone Cove, Maine, deputy sheriff Dwayne Hopper is on the night shift at the police station. He discovers that one of the prisoners in the holding cell is Ronald Perkins, a local psychiatrist and a suspect in the disappearance of 14 children over the past 10 years, including Hopper's young son. Interrogating Perkins, Hopper learns that the mad psychiatrist has built an army of 14 people brainwashed through cult-like methods to protect him from Perkins' parents' killers. Investigating, Hopper and the police unwittingly unleash his followers on the small town, and a night of terror beings as the 14 super-strong, zombie-like warriors wreck havoc with only one thing on their mind: "Kill for Mr. Perkins."