In St. John College, the freshmen and best friends Luke and Roger meet the sexy blond cousins Lilly and Constance in the laundry of their building. They are next-door neighbors, and the experienced girls invite the young men to visit them anytime. Lilly forgets a package of coins in the laundry, and Luke goes to their room to return it. The room is empty, and he sneaks around, when the two girls arrive. Luke hides himself in the wardrobe, and through an opening, he sees Lilly with many tentacles on her breast. Luke tries to convince his friends that the girls are aliens, planning to attack Earth, but nobody believes in him. Meanwhile, some friends of them are found dead, with the internal organs completely frozen.

Six friends take a road trip to Galveston in an RV for the wedding of their friend, Kelly. The driver, Johnny, gets lost and they arrive in the small town of Lovelock and his friends Sara, Kate, Melody, Christian, and David, decide to spend the night in the Bed and Breakfast owned by the creepy Mr. Robert Wise. David has an argument with the chef of the inn, Henri, and when the chef is found dead and Mr. Wise has a heart attack in the middle of the night, the local Sheriff suspects the group of travelers and tells his Deputy, Enus to seize the keys to their RV and stay in Lovelock for the duration of the investigation. Then the Sheriff arrests "The Mysterious Drifter" who soon becomes his prime suspect. When the clumsy Johnny accidentally breaks an ancient exotic wooden box belonging to Mr. Wise, he releases the terrible, monstrous "Kuman Thong" and the evil spirit held inside escapes and possesses all the local town folk...

The undertaker Fred is bankrupted and misses his former wife Helen. She has left him and is going to marry Captain Winston...

In Rome, after the abduction of a British tourist, the police inspector Anna Mari is contacted by the criminal, who self-entitles The Card Player, challenging the police department to dispute a video poker with him where the prize would be the life of the victim. The Chief of Police refuses to participate and the victim is tortured and killed in front of an Internet web cam. The British detective John Brennan is assigned to investigate the case and when another woman is kidnapped, they invite the addicted player Remo to play for the police. Anna and John lead the investigation trying to disclose who might be the serial-killer.

After an overly ambitious businessman transports an 80-foot python to the United States, the beast escapes...

A fertility clinic visit becomes an unfathomable nightmare for a woman who's impregnated with the devil's DNA.

Blade finds himself alone surrounded by enemies, fighting an up hill battle with the vampire nation and now humans. He joins forces with a group of vampire hunters whom call themselves the Nightstalkers. The vampire nation awakens the king of vampires Dracula from his slumber with intentions of using his primitive blood to become day-walkers. On the other side is Blade and his team manifesting a virus that could wipe out the vampire race once and for all. In the end the two sides will collide and only one will come out victorious, a battle between the ultimate vampire whom never knew defeat, facing off against the greatest vampire slayer.

In New York, the ambitious Dr. Jack Byron and his associate Gordon Mitchell present the research of his assistant Sam Rogers to the CEO and board of directors of a corporation to sponsor a scientific expedition to Borneo. The objective is to find a flower, Blood Orchid, that flourishes for a couple of weeks every seven years and could be a fountain of youth, prolonging the expectation of life of human beings. They are succeeded and once in Borneo, they realize that it is the raining season and there is no boat available to navigate on the river. They pay US$ 50,000.00 to convince Captain Bill Johnson and his partner Tran to sail to the location. After an accident in a waterfall, the survivors realize that a pack of anacondas have gathered for mating and their nest is nearby the plantation of Blood Orchid, which made them bigger and bigger.

In the 1580's English colonists arrive in what was to become North Carolina and find supernatural terror.