Robert Neville, a doctor, due to an experimental vaccine, is the only survivor of an apocalyptic war waged with biological weapons. The plague caused by the war has killed everyone else except for a few hundred deformed, nocturnal people calling themselves "The Family". The plague has caused them to become sensitive to light, as well as homicidally psychotic. They believe science and technology to be the cause of the war and their punishment, and Neville, as the last symbol of science, the old world, and a "user of the wheel", must die. Neville, using electricity, machinery, and science attempts to hold them at bay.

A doctor, scientist, organist, and biblical scholar, Dr. Anton Phibes, seeks revenge on the nine doctors he considers responsible for his wife's death.

As Aunt Alice, Ruth Gordon applies for the job of housekeeper in the Tucson, Arizona home of widow Claire...

The radiation from a fallen satellite might have caused the recently deceased to rise from the grave and seek the living to use as food. This is the situation that a group of people penned up in an old farmhouse must deal with.

Satan-worshiper Prince Prospero invites several dozen of the local nobility to his castle for protection against an oncoming plague, the Red Death. Prospero orders his guests to attend a masked ball and, amidst a general atmosphere of debauchery and depravity, notices the entry of a mysterious hooded stranger dressed all in red. Believing the figure to be his master, Satan, Prospero is horrified at the revelation of his true identity.

In a tale that almost redefines sibling rivalry, faded actresses Blanche and 'Baby' Jane Hudson live together. Jane was by far the most famous when she performed with their father in vaudeville but as they got older, it was Blanche who became the finer actress, which Jane still resents. Blanche is now confined to a wheelchair and Jane is firmly in control. As time goes by, Jane exercises greater and greater control over her sister, intercepting her letters and ensuring that few if anyone from the outside has any contact with her. As Jane slowly loses her mind, she torments her sister going to ever greater extremes.

Three stories adapted from the work of Edgar Allen Poe. A man and his daughter are reunited, but the blame for the death of his wife hangs over them, unresolved. A derelict challenges the local wine-tasting champion to a competition, but finds the man's attention to his wife worthy of more dramatic action. A man dying and in great pain agrees to be hypnotized at the moment of death, with unexpected consequences.

In Victorian England, the uncle of orphaned niece Flora and nephew Miles hires Miss Giddens as governess to raise the children at his estate with total independence and authority. Soon after her arrival, Miss Giddens comes to believe that the spirits of the former governess Miss Jessel and valet Peter Quint are possessing the children. Miss Giddens decides to help the children to face and exorcise the spirits.

Francis Barnard goes to Spain, when he hears his sister Elizabeth has died. Her husband Nicholas Medina, the son of the brutest torturer of the Spanish Inquisition, tells him she has died of a blood disease, but Francis finds this hard to believe. After some investigating he finds out that it was extreme fear that was fatal to his sister and that she may have been buried alive! Strange things then start to happen in the Medina castle.

After a long journey, Philip arrives at the Usher mansion seeking his loved one, Madeline. Upon arriving, however, he discovers that Madeline and her brother Roderick Usher have been afflicted with a mysterious malady: Roderick's senses have become painfully acute, while Madeline has become catatonic. That evening, Roderick tells his guest of an old Usher family curse: any time there has been more than one Usher child, all of the siblings have gone insane and died horrible deaths. As the days wear on, the effects of the curse reach their terrifying climax.

Professor Henry Jarrod is a true artist whose wax sculptures are lifelike. He specializes in historical tableau's such a Marie Antoinette or Joan of Arc. His business partner, Matthew Burke, needs some of his investment returned to him and pushes Jarrod to have more lurid exposes like a chamber of horrors. When Jarrod refuses, Burke set the place alight destroying all of his beautiful work in the hope of claiming the insurance. Jarrod is believed to have died in the fire but he unexpectedly reappears some 18 months later when he opens a new exhibit. This time, his displays focus on the macabre but he has yet to reproduce his most cherished work, Marie Antoinette. When he meets his new assistant's beautiful friend, Sue Allen, he knows he's found the perfect model - only unbeknown to anyone, he has a very particular way of making his wax creations.

Sherlock Holmes investigates when young women around London turn up murdered, each with a finger severed off. Scotland Yard suspects a madman, but Holmes believes the killings to be part of a diabolical plot.

Sherlock Holmes investigates a series of deaths at a castle with each foretold by the delivery of orange pips to the victims.

Sherlock Holmes takes on a case that the press has dubbed the pajama suicides. Eminent men are going to bed in the safety of their own homes, with everything seemingly being normal, only to commit suicide in the night. Holmes fakes his own death in the hopes of giving him a freer hand in the investigation and is convinced that a woman, a female Moriarty as he describes her, is behind the deaths. The dead men were all eminent and very wealthy. He impersonates a wealthy retired Indian military officer in the hope of drawing out the woman and he soon meets Adrea Spedding but she quickly sees through his disguise and proves herself to be the challenge Holmes predicted she would be. She is a worthy adversary and soon traps him setting him up in a carnival shooting gallery that seems to assure his death.

An escaped Devil's Island convict uses miniaturized humans to wreak vengeance on those that framed him.

When a nobleman is murdered, a professor of the occult blames vampires; but not all is what it seems.

A circus' beautiful trapeze artist agrees to marry the leader of side-show performers, but his deformed friends discover she is only marrying him for his inheritance.