Emily tells her son Paul, now six years old, the story of his life - how she sought motherhood, to be a mom without a husband, to raise a perfect, exceptional child, whom she calls Loverboy. In flashbacks told around a pretend car trip they take - so he can practice driving - we see Paul's infancy, their fun together (sometimes with a manic edge), and his growing desire to go to school and be with other kids. We also flash back to Emily's childhood, with parents so bound up with each other that she's virtually ignored. Is Emily going to be able to let Paul be with others? Or, can she, as in the David Bowie song she sings at a school talent show, construct a life on Mars?

In Manhattan, 10-year-old Gabe finds his first love when he meets his former kindergarten mate, eleven-year-old Rosemary, in his karate classes. Confused with his new feelings and with the divorce process of his beloved parents, Leslie and Adam, he experiences the delightful unknown sensation of being in love for the first time.

In the perfectly normal town of Louisville, KY, there is a perfectly normal man living the perfect life. David Dailey is a man who has it all: A great career, a community that adores him, and an enduring marriage. But beneath the surface, David's idyllic world is crumbling. He's haunted by a series of mysterious notes that warn of an imminent fall from grace. His sultry wife Susan is hell-bent on expanding the horizons of their sex life - with or without him. His longtime assistant Whit is gunning for his job. And he finds himself increasingly attracted to Melody Carpenter, a curious stranger he instinctively trusts because she doesn't know him well enough to betray him. Complicating matters, Melody's jilted boyfriend Sean, a charming and talented trust fund baby, regards David and Melody's fledgling friendship with contempt. As his jealousy seethes deeper, he concocts a devious plan to win her back...

Elizabeth Masterson, a dedicated doctor in San Francisco, had almost no time for anything. When her sister with two kids set her up on a date, she gets into a tragic car crash and gets in a coma. Meanwhile, an landscape architect named David Abbott moves into San Francisco and coincidentally, into Elizabeth's apartment for rent. While at the apartment, Elizabeth's spirit haunts him. She doesn't remember who she is, who her family is, and what she did - All that she remembered was her apartment and where everything was. To settle the arguments, David agrees to figure out who Elizabeth really is. When they get close to figuring out who she is, they eventually find love with one another and as they finally know who she really is, they learn that fate really has put them both together.

Chris Brander has always been friends with Jamie Palamino, but now decides it is time to take his relationship to the next step. The problem is, is that Jamie still wants to be 'Just Friends'. When he runs away and moves to L.A., he becomes a attractive music manager, who everyone wants. When his jet catches fire and is forced to land, when flying to Paris with his newest singing sensation, Samantha James, he ends up back home. To his surprise, he encounters Jamie again, and sets out to be more than 'Just Friends' this time.

Straight-laced Rose breaks off relations with her party girl sister, Maggie, over an indiscretion involving Rose's boyfriend. The chilly atmosphere is broken with the arrival of Ella, the grandmother neither sister knew existed.

Rachel and Heck, long time friends and lovers, finally tie the knot, and during the celebration, Rachel starts a friendship with their florist, Luce. And while Rachel originally intended to match her new friend, Luce, up with her husband's friend, Cooper, she soon finds out that Luce is a lesbian. During the course of their friendship, Rachel starts to question her own sexuality. And though she comes to realize she may have feelings for her new friend, Rachel must decide who she will ultimately find the most happiness with: Heck, her new husband who is also adored by her family, or Luce, who has turned her life and everything she thought she knew about love upside down.