When Connor Macleod sees his old friend Rachel die in an explosion, he's had it with his immortal life and the endless pain it brings him and those he loves. He locks himself inside the Sanctuary, a Watcher-organized retreat stationed on holy ground, where immortals who are tired of the game can go to forever escape it, as well as to ensure that The Prize never falls into the wrong hands. But when an old enemy, Jacob Kell, and his posse of assassins attack the Sanctuary and kill everyone there but Connor, he is forced out into the open and into battle. Kell and Connor were friends once, and knew each other back when Connor was cast from Glenfinnan; he returned when news came that his mother was to be burned at the stake, and in the attempt to free her, Kell was killed by none other than Connor himself, and became an immortal, bitter with hate, and devoted to making Connor's life a living hell...

Brothers Jake and Ethan witness something crashing to earth and discover that it is a satellite of some kind. Being broke, they collect it and sell it to the local scrap dealer, Earl. Earl, meanwhile, has built an 18 foot "Golem" out of scrap iron to be used in the local town parade. The satellite is infected with some type of space bacteria which feeds on metal and also causes said metal to become animated. The result is that the Golem becomes infected, comes alive, and begins killing people by sucking the metals from their body with just a touch. Jake must find a way to defeat the Golem and save the town.

When Henry DeTamble meets Clare Abshire in a Chicago library they both understand that he is a time traveller, but she she knows much more than this about him as he has not yet been to the times and places where they have met before. He falls in love with her, as she has already with him, but his continuing unavoidable absences time travelling - and then returning with increasing knowledge of their future - makes things ever more difficult for Clare.

Peyton and Barney are fun loving high school students working on a science project with white mice. When one of the mice begins to move food toward itself with out touching it, Barney finds he has accidently discovered a formula for telekinetic powers. Now, how much trouble can a high school boy who can move things with just his mind get into?