Rose is involved in a motorcycle accident, and has experimental surgery performed in order to save her life. However, she develops a taste for blood. Her victims grow in number as well as madness, turning the city into chaos.

A Seattle history professor, drawn back to his estranged family on the Oregon coast to execute his late mother's estate, is reaquainted with his best friend from childhood, with whom he has a long-awaited tryst. Caught in an accelerating series of events, he discovers aspects of his father's New Age cult which take on a dangerous and apocalyptic significance.

The uncle of an executed murderess relates four stories of his hometown, Oldfield, to a reporter: an elderly man pursues a romance with a younger woman, even to the grave and beyond...a wounded man on the run from creditors is rescued by a backwoods hermit with the secret to eternal life...a glass-eating carny pays the ultimate price for looking for love on the outside...and Civil War soldiers are held captive by a household of orphans with strange intentions for them.

In Edinburgh in 1831, Dr. Wolfe MacFarlane runs a medical school where Donald Fettes is a student. Fettes is interested in helping a young girl who has lost the use of her legs. He is certain that MacFarlane's surgical skills could be put to great use but he is reluctant to do so. The good Dr. MacFarlane has a secret that soon becomes all too obvious to young Fettes, who has only recently been promoted as his assistant: he has been paying a local cabbie, John Gray, to supply him with dead bodies for anatomical research. Gray constantly harasses MacFarlane and clearly has a hold over him dating to a famous trial many years before where Gray refused to identify the man for whom he was robbing graves. Fettes isn't aware of any of this but soon realizes exactly how Gray obtains the bodies they use in their anatomy classes.

Four young adult siblings try to fend for themselves after the mysterious death of their parents. But they harbor some dark secrets which include abducting and killing strangers, and feeding them to a mysterious 'thing' living in their cellar.

It is said in heaven above there is a book that holds the time line every human will spend on earth. Once you have passed this time your subconscious becomes your conscious and you can see the signs of IT in the black cape that subliminally lead you to your demise.

In Manhattan, when a client is bitten by a rat in the dressing room of the Garsons Department Store and contracts Weil's disease, the manager Susan Costello is assigned to hire and give all the necessary support to the best exterminator in New York, Jack Carver. The efficient Jack and his assistant Ty find a colony of mutant rats and try to convince the health department administrator and former partner of Jack, Ray Jarrett, how serious the infestation is. But the politician Ray is interested in covering the problem to protect economical interests of powerful groups.

Horror movie actor Paul Toombes, famous for playing "Dr. Death," suffers a nervous breakdown before going to England to do a TV series. Cast and crew members start dying the way characters did in Toombes' old movies.

Dr. Cross, a psychiatrist, is treating a young woman, Janet Stewart, who is in a coma-state, brought on when she heard loud arguing, went to her window and saw a man strike his wife with a candlestick and kill her. As she comes out of her shock, she recognizes Dr. Cross as the killer. He takes her to his sanitarium and urged by his nurse/lover, Elaine Jordan, gives Janet an overdose of insulin. But he can't bring himself to murder her in cold blood and asks Elaine to get the medicine to save her. She refuses, they argue, and he strangles her. He saves Janet's life, but now faces two murder charges.