On the day after his fortieth birthday, the family man and computer analyst George Grieves goes to the Mt. Abaddon Hospital for a routine procedure of colonoscopy with Dr. Sharazi. Along his birthday party, his friends and family tell many cases of medical errors, and George is worried about. After the surgery, George finds that his surgery had complications because of a homonymous patient, and he had received a thoracoscopic sympathectomy instead. While interned, George discloses bizarre and dark secrets about the East Wing of the hospital while his wife and family have to take a decision about his fate.

Jim Davis is an ex-Army Ranger who finds himself slipping back into his old life of petty crime after a job offer from the LAPD evaporates. His best friend is pressured by his girlfriend Sylvia to find a job, but Jim is more interested in hanging out and making cash from small heists, while trying to get a law enforcement job so he can marry his Mexican girlfriend.

In a dark and decadent area of São Paulo, the exiled Americans Sinatra and his son Paul own a brothel. Paul is a compulsive gambler addicted in cocaine and his father is married with the former prostitute Angie, and they have a little son. When a client is killed by his wife in their establishment, they find a suitcase with drugs. In the night that they have scheduled a negotiation with African buyers, their African liaison dies while having sex with the travesty Nazda. Sinatra proposes to the Nigerian dishwasher of the brothel, Wemba, to travel to the harbor of Santos, close the business with the drug dealers and in return he would receive a large amount. Wemba accepts but while returning to his car in the harbor, he is attacked by two smalltime thieves and passes out. His lack of contact with Sinatra and Paul leads to a sequence of misunderstandings with a tragic end.

Tom Dobbs, comedic host of a political talk show - a la Bill Maher and Jon Stewart - runs for President of the US as an independent candidate who, after an issues-oriented campaign and an explosive performance in the final debate, gets just enough votes to win. Trouble is he owes his victory to a computer glitch in the national touch-screen voting system marketed by Delacroy, a private company with a rising stock price. To protect their fortune, Delacroy executives want to keep the glitch a secret, but one programmer, Eleanor Green, wants Dobbs to know the truth. Can she get to him?

Following the death of her father, a teenage Dot moves into the home of her godparents and their teenage daughter Nina. Dot arrives wrapped up in the silence of being deaf-mute. She finds a different kind of silence waiting for her in her new home, for this home is a place with a dark secret involving Nina and her father. At first, Dot and Nina seem to be polar opposites. However, they gradually realize how much they have in common. Bringing them together catalyzes a series of events in which both reveal their secrets and shed their double lives. A violent consummation almost destroys them. Yet they find hope for the future in the quiet after the storm.

Struggling private investigator Louis Simo treats his work more as a means to make a living than a want to do right by what few clients he has. Through connections with the investigation firm for which he used to work, Simo is hired by Helen Bessolo to investigate the death of her son, actor . Reeves was best known for his title role in , a role which he always despised, in part since it typecast him as a "cartoon", despite it bringing him a certain fame. His June 16, 1959 death by a single gunshot wound while in his bedroom in his Los Angeles home was ruled a suicide by the police, the death which occurred when the house was filled with people. Reeves' story is told in part in flashback as Simo, who is trying to make a name for himself with this case, talks to or tries to talk to some of the players involved, most specifically the wife of MGM General Manager ...

Five men wake up in a locked-down warehouse with no memory of who they are. They are forced to figure out who is good and who is bad to stay alive.