When the bad boy John inherits an isolated house in an island, he invites his brother and student of veterinary Matt and his girlfriend Nikki together with their common friends Sara and Noah to fly with him in his hydroplane and spend a couple of days having good time in the place. Later Sara is attacked by a dog and they recall that in the other side of the island there was a facility for training dogs that had been shutdown to avoid a rabies outbreak. While walking through the woods, they find a man called Luke, who sailed with his girlfriend Jenny to the island, covered of blood and Luke is killed by a pack of hounds. The group runs to the house and the animals put the place under siege, and they try to find a means of escape. When the survivors reach the compound, they disclose that the dogs have been genetically redesigned to become a breed of killers.

When millionaire businessman Ted Billings (Glenn Morshower) double-crosses his partners in a weapons deal...

A gang member, suffering from severe memory loss, searches for his brother's murderer. He secretly enlists the aid of the investigating Detective, while other members of his gang are mysteriously and sadistically murdered.

A reporter witnesses a brutal murder, and becomes entangled in a mystery involving a pair of Siamese twins who were separated at birth, one of them forced to live under the eye of a watchful, controlling psychiatrist.

The school teacher Amy has been proposed by her boyfriend Nick early in the morning and she promises her answer later in the afternoon. After her class, while coming back home, Nick has a car accident in a crossroad with a truck driven by Lucas Dylan. He breaks his leg and an ambulance takes him to the hospital. Amy has a phobia about hospitals, but she gets a taxi and goes to the nearest hospital. However, Nick is not there, and she meets Lucas, who is also looking for his sister that has disappeared in the same weird circumstance. They decide to team up and search together where the victims might have been interned, while Amy experiences the most bizarre and scary situations.