In 1989, in Washington, the friends George, Max and Ricky are aspirant musicians that play in a band in their leisure time. They work as cooks in the Sans Asylum to earn money to pay their bills, including renting a studio to record their songs. The asylum is located in an isolated area and is monitored by a team led by the security guard J.B. The deranged inmates are criminals and they take pills to stay calm. One day, George has a concert during the night but J.B. asks him to arrive early in the morning to receive the supplies for the kitchen. George leaves his girlfriend Lynn without sleeping and heads to the asylum. While he is preparing the meals for the insane inmates with his colleagues, there is a storm and a power outage in the area and the monitoring system fails. With the mental hospital in the darkness, the inmates led by the cruel Harry Green attack the guards and staff. George and the other kitchen workers hide from the horde of violent madmen. Will they survive?

Eight haunted people meet and fall apart - looking for redemption in each other. Jim is throwing watermelons off his office roof. He's testing the effect for a possible suicide. But then there is Sue on an adjacent roof about to jump herself. They meet, delay their departure and set off searching for other ways out than down. Sue's ex-boyfriend, Dean, is struggling with his creativity. His paintings are getting panned and his poetry ripped apart. He needs a muse - and who better than Gina, the experimental prostitute with dodgy legs who lives next door. However, Dean soon finds out that Gina never does anything for free. After a short fling with Dean, Olly is lost in a world of sexual confusion when forced to look after his deaf-mute brother Chris for the day. Olly discovers that not only does Chris has gay feelings too, but is more comfortable with them than he is. They embark on a searing quest through Soho's gay community to help Chris loose his virginity...

As a major heist approaches and with betrayal all around him, a respected crime boss has to summon all his street nous and killer instinct as he fights for survival.