Nate, a 19 year old film student, and Margaret, a 52 year old spinster, are best friends in an odd, quirky, totally working kind of way... until Nate's audacious classmate Darla sets him up on a date with James. Nate's new life shakes apart his friendship with Margaret, just as she is trying to start a career as a stand-up comedian.

Socially-challenged hitman Charles lives in Cannes and wants to retire with a yacht and a woman in tow. He has no experience with either until he lets his cleaning lady (delectable Essex-girl Lisa) into his life, but he doesn't bank on her vile boyfriend Denny or con-artists Simon and Ray stealing a two million quid nest egg from the boot of his car. Charles hunts them down across the Cote d'Azur whilst pursued by his rival Clancy who is incensed by the fact that Charles might actually be retiring.

When Eric and Marsha break off their long-term relationship, journalist Eric is able to weather it pretty well. He still has his long time canine companion Gabe, and his boss, Ms Andrews, wants to send him to London to open an office. But first Ms Andrews says Eric must find out the true identity of the best-selling author R L Dutton. A bigger obstacle for Eric's trip, however, comes from his dog. Gabe does not want to face six months in quarantine with big pit bulls and mastiffs waiting for an OK to the UK. Getting ideas from a pretty TV host, Gabe acts as Cupid Dog, doing his best to bring Eric and their neighbor Sara together. Gabe's plan works, only to go up in smoke when Eric realizes Sara is the mysterious author. Now Sara thinks Eric was just using her for a story before leaving for London. Gabe the Cupid Dog must go to new lengths to get Sara and Eric to tie the "leash."