Local mechanic Jake LaFond's life is suddenly disrupted when mysterious parasites transform the law-abiding citizens of his quaint hometown into hoards of cannibalistic zombies. Isolated from the outside world by an accident on the only road out of town, Jake turns to Alex, his ex-girlfriend, for help. Together they try to solve the mystery behind this rapidly spreading infection. As the town grows deadlier by the moment, Jake's gun-toting rival, Randy, becomes the third person in this trio of unlikely heroes and the battle is on. Between blood hungry grandmothers and lethal domestic animals, Jake, Alex and Randy must fight to make it through the night. Can they survive?

In Edinburgh in 1831, Dr. Wolfe MacFarlane runs a medical school where Donald Fettes is a student. Fettes is interested in helping a young girl who has lost the use of her legs. He is certain that MacFarlane's surgical skills could be put to great use but he is reluctant to do so. The good Dr. MacFarlane has a secret that soon becomes all too obvious to young Fettes, who has only recently been promoted as his assistant: he has been paying a local cabbie, John Gray, to supply him with dead bodies for anatomical research. Gray constantly harasses MacFarlane and clearly has a hold over him dating to a famous trial many years before where Gray refused to identify the man for whom he was robbing graves. Fettes isn't aware of any of this but soon realizes exactly how Gray obtains the bodies they use in their anatomy classes.

Four young adult siblings try to fend for themselves after the mysterious death of their parents. But they harbor some dark secrets which include abducting and killing strangers, and feeding them to a mysterious 'thing' living in their cellar.

It is said in heaven above there is a book that holds the time line every human will spend on earth. Once you have passed this time your subconscious becomes your conscious and you can see the signs of IT in the black cape that subliminally lead you to your demise.

In Manhattan, when a client is bitten by a rat in the dressing room of the Garsons Department Store and contracts Weil's disease, the manager Susan Costello is assigned to hire and give all the necessary support to the best exterminator in New York, Jack Carver. The efficient Jack and his assistant Ty find a colony of mutant rats and try to convince the health department administrator and former partner of Jack, Ray Jarrett, how serious the infestation is. But the politician Ray is interested in covering the problem to protect economical interests of powerful groups.

Horror movie actor Paul Toombes, famous for playing "Dr. Death," suffers a nervous breakdown before going to England to do a TV series. Cast and crew members start dying the way characters did in Toombes' old movies.

Valentine's Day 1988: At the school dance, geeky Jeremy Melton bravely faces one rejection after the other when asking four popular girls to dance with him. A fifth girl, plump and insecure, agrees, but they end up making out under the bleachers. When a group of school bullies catches them, the girl claims that Jeremy attacked her. This causes them to strip off his clothes and beat him up in front of the entire school. Flash forward to 2001. We meet the five girls who were in that school gym: Kate, Paige, Shelly, Lily and the formerly plump Dorothy. They are all in their 20's now and trying to sort out their love lives, which is appropriate, since Valentine's Day is coming up. After a disastrous date with a loser, one of the girls, a pre-med student, is murdered by a Cherub-mask wearing killer who sent her a death threat in the form of a Valentine card prior to the attack...

When Frank and Julie move to a small isolated town with their son Sam, both Julie and Sam become ill. Driven by terrifying nightmares of torture that come true Frank begs a local midwife Helen to care for Sam as he desperately searches for a way to stop this curse on his family. When he discovers they are being tortured by the vengeful spirit of a child that was buried alive years earlier, Frank is pushed to the brink of madness as he tries to stop the ghost and save his dying family.